CD20 / MS4A1 (B-Cell Marker)(L26), CF647 conjugate, 0.1mg/mL Antibody | BNC470766-100

CD20 / MS4A1 (B-Cell Marker)(L26), CF647 conjugate, 0.1mg/mL Antibody | BNC470766-100| Gentaur Distribution US, UK & Europe

Summary.: This antibody recognizes a protein of 30-33 kDa, which is identified as CD20. Its epitope is located in the cytoplasmic domain of CD20 and was, therefore, ascribed as CD20cy in the 5th Workshop. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This MAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue, germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkin s disease, particularly of lymphocyte predominant type..

Conjugate: CF647.

Storage Buffer: PBS, 0.1% BSA, 0.05% azide.

Storage Temperature: 2°C to 8°C.

Application: Flow (verified)|IF (verified)|IHC, FFPE (verified)|WB (verified).

Stability: Stable at room temperature or 37°C (98°F) for 7 days.