CD20 / MS4A1 (B-Cell Marker) (IGEL/1497R), 1mg/mL Antibody | BNUM1497-50

CD20 / MS4A1 (B-Cell Marker) (IGEL/1497R), 1mg/mL Antibody | BNUM1497-50| Gentaur Distribution US, UK & Europe

Summary.: This antibody recognizes a protein of 30-33 kDa, which is identified as CD20. It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This MAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue, germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkin's disease, particularly of lymphocyte predominant type. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. .

Conjugate: Purified, BSA-free.

Storage Buffer: PBS, no BSA, no azide.

Storage Temperature: 35°C to -5°C .

Application: Flow (verified)|IHC, FFPE (verified).

Stability: Stable at room temperature or 37°C (98°F) for 7 days.