CD1e Antibody | F52013-0.08ML

CD1e Antibody | F52013-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, IHC, FACS, IF, ELISA

Buffer: N/A

Limitation: This CD1e antibody is available for research use only.

Purity: Antigen affinity

Description: CD1E encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members.

Immunogen: A portion of amino acids 184-212 from the human protein was used as the immunogen for this CD1e antibody.

Storage: Aliquot the CD1e antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.