CD1b Antibody | V2028SAF-100UG

CD1b Antibody | V2028SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: RIV12

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: ELISA, FACS, IF

Buffer: N/A

Limitation: This CD1b antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: This antibody recognizes CD1b, a 44kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1b molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. It is also expressed in interdigitating cells.

Immunogen: Human peripheral lymphocytes were used as the immunogen for this CD1b antibody.

Storage: Store the CD1b antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).