CD1b(100-1A5), 0.2mg/mL Antibody | BNUB1044-100

CD1b(100-1A5), 0.2mg/mL Antibody | BNUB1044-100| Gentaur Distribution US, UK & Europe

Summary.: The mouse monoclonal antibody recognizes CD1b, a 44 kDa type I glycoprotein associated with beta2-microglobulin (Workshop IV; Code T015). It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL..

Conjugate: Purified, with BSA.

Storage Buffer: PBS, 0.05% BSA, 0.05% azide.

Storage Temperature: 2°C to 8°C.

Application: Flow, surface (published).

Stability: Stable at room temperature or 37°C (98°F) for 7 days.