Description
CD1a Antibody | F53637-0.1ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In ascites with 0.09% sodium azide
Format: Ascites
Clone: 437CT28.2.1
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: WB, ELISA
Buffer: N/A
Limitation: This CD1a antibody is available for research use only.
Purity: Ascites
Description: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
Immunogen: A portion of amino acids 76-104 from the human protein was used as the immunogen for this CD1a antibody.
Storage: Aliquot the CD1a antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.