CD19 Antibody / B-lymphocyte marker | V2389SAF-100UG

CD19 Antibody / B-lymphocyte marker | V2389SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: CVID3/429

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: FACS, IF

Buffer: N/A

Limitation: This CD19 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: CD19 is expressed on follicular dendritic cells and B cells. It is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase. [Wiki]

Immunogen: Human CD19 recombinant full length protein was used as immunogen for this CD19 antibody.

Storage: CD19 antibody with azide can be stored at 2-8oC. The azide-free format should be aliquoted and stored at -20 °C or colder.