Description
CD146 Antibody / MCAM / MUC18 | V8923-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: MCAM/3179
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: ELISA
Buffer: N/A
Limitation: This MCAM antibody is available for research use only.
Purity: Protein A/G affinity
Description: The human MCAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated Mel-CAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. MCAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. MCAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Immunogen: Recombinant human MCAM/CD146 protein was used as the immunogen for the MCAM antibody.
Storage: Aliquot the MCAM antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
