CD146 Antibody / MCAM / MUC18 | V8923-20UG

CD146 Antibody / MCAM / MUC18 | V8923-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: MCAM/3179

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: ELISA

Buffer: N/A

Limitation: This MCAM antibody is available for research use only.

Purity: Protein A/G affinity

Description: The human MCAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated Mel-CAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. MCAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. MCAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.

Immunogen: Recombinant human MCAM/CD146 protein was used as the immunogen for the MCAM antibody.

Storage: Aliquot the MCAM antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.