CD146 Antibody / MCAM / MUC18 | V2698-100UG

CD146 Antibody / MCAM / MUC18 | V2698-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: C146/634

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: FACS, IF, IHC-P

Buffer: N/A

Limitation: This CD146 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: The human CD146 gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. CD146 expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. It is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.

Immunogen: Recombinant human protein was used as the immunogen for the CD146 antibody.

Storage: Store the CD146 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).