CD146 Antibody / MCAM / MUC18 | V2189-20UG

CD146 Antibody / MCAM / MUC18 | V2189-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: OJ79c

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: FACS, IF

Buffer: N/A

Limitation: This MUC18 antibody is available for research use only.

Purity: Protein G purified antibody

Description: The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. MUC18 expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. MUC18 / CD146 is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.

Immunogen: Recombinant human protein was used as the immunogen for this MUC18 antibody.

Storage: Store the MUC18 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).