Description
CD14 Antibody | V3758-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Format: Purified
Clone: LPSR/2385
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: WB, FACS, IHC-P
Buffer: N/A
Limitation: This CD14 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: Recognizes a protein of 55kDa, identified as Cluster of Differentiation 14 (also known lipopolysaccharide receptor or LPSR). CD14 is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. It is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation.
Immunogen: A human recombinant partial protein (within amino acids 25-148) was used as immunogen for this CD14 antibody.
Storage: CD14 antibody with azide can be stored at 2-8oC. The azide-free format should be aliquoted and stored at -20 °C or colder.
