Description
CD14 Antibody | F49569-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IHC, FACS, ELISA
Buffer: N/A
Limitation: This CD14 antibody is available for research use only.
Purity: Purified
Description: In concert with LBP, CD14 binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. [UniProt]
Immunogen: A portion of amino acids 292-322 from the human protein was used as the immunogen for this CD14 antibody.
Storage: Store at 4oC for up to one month. For long term, aliquot the CD14 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
