CD137L Antibody / 4-1BBL / TNFSF9 | V8184-100UG

CD137L Antibody / 4-1BBL / TNFSF9 | V8184-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: CD137L/1547

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: FACS, IHC-P

Buffer: N/A

Limitation: This CD137L antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: TNFSF9 / 4-1BBL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9 / 4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9 / 4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. It has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine is required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.

Immunogen: A recombinant full-length human CD137L protein was used as the immunogen for the CD137L antibody.

Storage: Store the CD137L antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).