CD137 Antibody / 4-1BB / TNFRSF9 | V8636SAF-100UG

CD137 Antibody / 4-1BB / TNFRSF9 | V8636SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: r4-1BB/4603

Host: Mouse

Clonality: Recombinant Mouse Monoclonal

Isotype: Mouse IgG2a, kappa

Species Reactivity: Human

Application: IHC-P

Application Details: Immunohistochemistry (FFPE): 2-4ug/ml for 30 minutes at RT

Application Note: Optimal dilution of the recombinant CD137 antibody should be determined by the researcher.

Purity: Protein G affinity chromatography

Description: CD137 belongs to the tumor necrosis factor receptor family and delivers a costimulatory signal to T lymphocytes. It is expressed on activated T cells and binds an inducible ligand that is found on B cells, macrophages and dendritic cells. Interactions between CD137 and its ligand are involved in antigen presentation and the generation of cytotoxic T cells. CD137 antibody may improve cancer treatment, and has been implicated in breast cancer, melanoma and lymphoma.

Immunogen: A portion of amino acids 19-188 from the human protein was used as the immunogen for the recombinant CD137 antibody.

Storage: Store the recombinant CD137 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).

Localization: Cell surface