Description
CD137 Antibody / 4-1BB / TNFRSF9 | V7531-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: CDLA137-1
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: IF, IHC-P
Buffer: N/A
Limitation: This CD137 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: CD137 belongs to the tumor necrosis factor receptor family and delivers a costimulatory signal to T lymphocytes. It is expressed on activated T cells and binds an inducible ligand that is found on B cells, macrophages and dendritic cells. Interactions between CD137 and its ligand are involved in antigen presentation and the generation of cytotoxic T cells. CD137 antibody may improve cancer treatment, and has been implicated in breast cancer, melanoma and lymphoma.
Immunogen: A recombinant human CD137 protein fragment within amino acids 19-188 was used as the immunogen for the CD137 antibody.
Storage: Store the CD137 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
