Description
CD137 (4-1BB) HEK293 Recombinant Cell Line | 60691 | Gentaur US, UK & Europe Disrtribition
Category: Immunotherapy/Cell Line
Application: This cell line is useful for CD137 binding assays or downstream CD137-dependent signaling events.
Background: Human CD137 (4-1BB; TNFRS9) is an inducible costimulatory molecule that activates T cells. CD137-CD137L mediated signaling has been shown to be important for proliferation, effector functions and survival of T cells. CD137 is also expressed in NK and NKT cells. Antibodies targeting CD137 activation in immune cells have demonstrated potent anti-tumor effects in cancer patients.
Description: Recombinant HEK293 cell constitutively expressing full length human CD137 (Genbank #NM_003811). Surface expression is confirmed by flow cytometry.
Product Type: Cell Line
Shippement Condition: -80°C (dry ice)
