Description
CD11b Antibody / MAC-1 | RQ5357 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol
Format: Purified
Clone: BCG-9
Host Animal: Rabbit
Clonality: Rabbit Monoclonal
Species Reactivity: Human
Application: IHC-P, WB
Buffer: N/A
Limitation: This CD11b antibody is available for research use only.
Purity: Affinity purified
Description: The ITGAM gene encodes the integrin alpha M chain, also called CD11b and MAC-1. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [RefSeq]
Immunogen: A synthetic peptide specific to human CD11b / ITGAM was used as the immunogen for the CD11b antibody.
Storage: Store the CD11b antibody at -20 °C.
