CD11b Antibody / MAC-1 | R32580

CD11b Antibody / MAC-1 | R32580 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Mouse

Application: WB

Buffer: Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide

Limitation: This antibody is available for research use only.

Purity: Antigen affinity

Description: Integrin alpha M (ITGAM) is one protein subunit that forms the heterodimeric integrin alpha-M beta-2 (aM/b2) molecule, also known as macrophage-1 antigen (Mac-1) or cluster of differentiation molecule 11b (CD11b). It is mapped to 16p11.2. ITGAM/CD11b has a role in vascular repair after mechanical arterial injury. It is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. What's more, ITGAM probably recognizes the R-G-D peptide in C3b, and it is also a receptor for fibrinogen, factor X and ICAM1.

Immunogen: A mouse recombinant protein corresponding to amino acids E260-T360 was used as the immunogen for the mouse CD11b antibody.

Storage: After reconstitution, the mouse CD11b antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.