CD11b Antibody | F40833-0.4ML

CD11b Antibody | F40833-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IHC, FACS, WB, ELISA

Buffer: N/A

Limitation: This CD11b antibody is available for research use only.

Purity: Antigen affinity

Description: CD11b is the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.

Immunogen: A portion of amino acids 253-282 from the human protein was used as the immunogen for this CD11b antibody.

Storage: Aliquot the CD11b antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.