Description
CD11a Antibody / LFA-1 | V2642-20UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Format: Purified
Clone: DF1524
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: FACS, IF, Functional studies
Buffer: N/A
Limitation: This CD11a antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: Recognizes a protein of 180 kDa, identified as CD11a (Leucocyte Workshop IV; Code 1524). CD11a complex with the beta 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses. This mAb potently blocks LFA-1 dependent homotypic cell aggregation.
Immunogen: Human CD11a protein was used as the immunogen for the CD11a antibody.
Storage: Store the CD11a antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
