CCND1 Antibody | F52187-0.4ML

CCND1 Antibody | F52187-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse, Rat

Application: WB, ELISA

Buffer: N/A

Limitation: This CCND1 antibody is available for research use only.

Purity: Antigen affinity

Description: Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin D1 forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. Mutations, amplification and overexpression of the gene encoding this protein, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.

Immunogen: A portion of amino acids 264-292 from the human protein was used as the immunogen for this CCND1 antibody.

Storage: Aliquot the CCND1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.