CBX2, GST-tag | 55011

CBX2, GST-tag | 55011 | Gentaur US, UK & Europe Disrtribition

Category: Methyl-lysine Reader/Protein

Application: Useful for protein binding assays, screening inhibitors, and selectivity profiling.

Background: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A Lys119, rendering chromatin heritably changed in its expressibility. Involved in sexual development, acting as activator of NR5A1 expression.

Description: Human chromobox homolog 2 (CBX2), also known as SRXY5 and cell division cycle associated 6 (CDCA6), GenBank Accession No. NM_005189, a.a. 2-90, with N-terminal GST-tag, MW=37.3 kDa, expressed in an E. coli cell expression system.

Product Type: Protein

Shippement Condition: -80°C