CBFB Antibody | F54434-0.08ML

CBFB Antibody | F54434-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: WB, IF, FACS, IHC-P

Buffer: N/A

Limitation: This CBFB antibody is available for research use only.

Purity: Antigen affinity purified

Description: Core-binding factor subunit beta is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters.

Immunogen: A portion of amino acids 61-90 from the human protein was used as the immunogen for the CBFB antibody.

Storage: Aliquot the CBFB antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.