Description
Cathepsin L Antibody | R30013 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS
Format: Ascites
Clone: CP-L14
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human, mouse, rat
Application: WB, IHC-F
Buffer: N/A
Limitation: This Cathepsin L antibody is available for research use only.
Purity: Ascites
Description: Cathepsin L is a lysosomal cysteine proteinase with a major role in intracellular protein catabolism. It also shows the most potent collagenolytic and elastinolytic activity in vitro of any of the cathepsins. Cathepsin L has been implicated in pathologic processes including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. Human liver cathepsin L consists of a heavy chain of about 25 kD and a light chain of about 5 kD. The gene is mapped to 9q21-q22. Cathepsin L is required for endothelial progenitor cell-induced neovascularization.
Immunogen: Procathepsin L isolated from the human lung cancer cell line EPLC 32M1 was used as the immunogen for this Cathepsin L antibody.
Storage: After reconstitution, the Cathepsin L antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
