Cathepsin K Antibody / CTSK | V7477SAF-100UG

Cathepsin K Antibody / CTSK | V7477SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: CTSK/2791

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This Cathepsin K antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.

Immunogen: A portion of amino acids 163-274 from the human protein was used as the immunogen for the Cathepsin K antibody.

Storage: Store the Cathepsin K antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).