Cathepsin F Inhibitor Screening Assay Kit | 79971

(No reviews yet) Write a Review
SKU:
412-79971
€1,179.00
Frequently bought together:

Description

Cathepsin F Inhibitor Screening Assay Kit | 79971 | Gentaur US, UK & Europe Disrtribition

Category: Protease/Assay Kit

Application: Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.

Background: Cathepsin F is a lysosomal cysteine protease that belongs to the papain-like superfamily. It is secreted by macrophages and is thought to play a role in processing and loading peptides into MHC complexes. Cathepsin F is also expressed in atherosclerotic lesions, where it degrades ApoB-100, triggering LDL aggregation. It has been implicated in tumor invasion and metastasis, inducing apoptosis of gastric cancer cells, and mutations in cathepsin F have been linked to Alzheimer's disease and Type B Kuf's disease.

Description: The Cathepsin F Inhibitor Screening Assay Kit is designed to measure the protease activity of Cathepsin F for screening and profiling applications. 

Product Type: Assay Kit

Shippement Condition: -80°C

View AllClose