Description
Cathepsin F Inhibitor Screening Assay Kit | 79971 | Gentaur US, UK & Europe Disrtribition
Category: Protease/Assay Kit
Application: Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Background: Cathepsin F is a lysosomal cysteine protease that belongs to the papain-like superfamily. It is secreted by macrophages and is thought to play a role in processing and loading peptides into MHC complexes. Cathepsin F is also expressed in atherosclerotic lesions, where it degrades ApoB-100, triggering LDL aggregation. It has been implicated in tumor invasion and metastasis, inducing apoptosis of gastric cancer cells, and mutations in cathepsin F have been linked to Alzheimer's disease and Type B Kuf's disease.
Description: The Cathepsin F Inhibitor Screening Assay Kit is designed to measure the protease activity of Cathepsin F for screening and profiling applications.
Product Type: Assay Kit
Shippement Condition: -80°C
