Caspase6, His-tag | 80113-2

Caspase6, His-tag | 80113-2 | Gentaur US, UK & Europe Disrtribition

Category: Apoptosis/Protein

Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling

Background: Caspase-6 is a member of the caspase (cysteine aspartate protease) family of proteins, and has been shown to be an executioner protein of apoptosis. Recent evidence shows that caspase-6 is involved in neurodegenerative diseases, such as Huntington's and Alzheimer's.

Description: Human Caspase 6 (CASP6), GenBank Accession No. NM_001226, full length, a.a. 1-293 (end), with C-terminal His-tag, expressed in an E. coli cell expression system. Pro-caspase-6 is activated by autocleavage to yield 20 kDa and 18 kDa proteins (large subunit) and an 11 kDa small subunit (His-tag) that dimerize to form the active enzyme.

Product Type: Protein

Shippement Condition: -80°C