Caspase-3 Antibody | F52416-0.08ML

Caspase-3 Antibody | F52416-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS pH 7.4 with 0.09% sodium azide

Format: Purified

Clone: 1262CT521.280.101

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB, ELISA

Buffer: N/A

Limitation: This Caspase-3 antibody is available for research use only.

Purity: Purified

Description: Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.

Immunogen: Purified His-tagged protein was used to produced this monoclonal Caspase-3 antibody.

Storage: Aliquot the Caspase-3 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.