Description
CASP9 Monoclonal Antibody | E-AB-22035 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human
Host: Mouse
Isotype: IgG
Application: WB, IHC-p, IF, IP
Research Area: Cancer, Cell Biology, Metabolism
Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Lead Time: 7~10 days
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic Peptide
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification: Protein A purification
Dilution: WB 1:500-1:2000, IHC 1:50-300, IF 1:50-1:200, IP 1:100-1:300
Conjugation: Unconjugated
Calculated Molecular Weight: 46 kDa
Observed Molecular Weight: 47-51 kDa
Clonality: Monoclonal
