CASP9 Monoclonal Antibody | E-AB-22035

CASP9 Monoclonal Antibody | E-AB-22035 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human

Host: Mouse

Isotype: IgG

Application: WB, IHC-p, IF, IP

Research Area: Cancer, Cell Biology, Metabolism

Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic Peptide

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification: Protein A purification

Dilution: WB 1:500-1:2000, IHC 1:50-300, IF 1:50-1:200, IP 1:100-1:300

Conjugation: Unconjugated

Calculated Molecular Weight: 46 kDa

Observed Molecular Weight: 47-51 kDa

Clonality: Monoclonal