Description
Canine Integrin alpha 11 beta 1 (ITGA11&ITGB1) Heterodimer Protein, His Tag&Tag Free | IT1-C52W9-1mg| Gentaur Distribution US, UK & Europe
Integrin alpha 11 beta 1 is a receptor for collagen. The alpha11 cDNA encodes a mature protein with a large 1120-residue extracellular domain that contains an I-domain of 207 residues and is linked by a transmembrane domain to a short cytoplasmic domain of 24 amino acids. The deduced alpha11 protein shows the typical structural features of integrin alpha-subunits and is similar to a distinct group of alpha-subunits from collagen-binding integrins.
Source: Canine ITGA11&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-C52W9) is expressed from human 293 cells (HEK293). It contains AA Asp 21 - Pro 1142 (ITGA11) & Asp 23 - Asp 728 (ITGB1) (Accession # A0A8I3S131-1 (ITGA11) & A0A8C0PYR6-1 (ITGB1) ).
Format: Powder.
Tag: C-10×His | Native.
Expression System: HEK293.
Expression Region: Asp 21 - Pro 1142 (ITGA11) & Asp 23 - Asp 728 (ITGB1).
Conjugate: Unconjugated.
Molecular Weight: 132.6 kDa (ITGA1) & 83.2 kDa (ITGB1).
Characteristics: Canine ITGA1&ITGB1 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA1 and ITGB1, has a calculated MW of 132.6 kDa (ITGA11) and 83.2 kDa (ITGB1). Subunit ITGA1 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus.
Purity: 90%.
Buffer: 50 mM Tris, 150 mM NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
