Description
Calponin 1 Antibody | V2465-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Format: Purified
Clone: CNN1/832
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human, Rat
Application: IF, IHC-P
Buffer: N/A
Limitation: This anti-Calponin antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist; a 34kDa form and a 29kDa form. Expression of the 29kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.
Immunogen: Recombinant human protein was used as the immunogen for the anti-Calponin antibody.
Storage: Store the anti-Calponin antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
