Calnexin Antibody | V3795-100UG

Calnexin Antibody | V3795-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: CANX/1543

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: ELISA, WB, IHC-P

Buffer: N/A

Limitation: This Calnexin antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: It recognizes a protein of 90kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.

Immunogen: A portion of amino acids 1-300 from the human protein was used as the immunogen for the Calnexin antibody.

Storage: Store the Calnexin antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).