Caldesmon / CAD Antibody HMW | V2941-100UG

Caldesmon / CAD Antibody HMW | V2941-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: SPM168

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P, WB

Buffer: N/A

Limitation: This Caldesmon antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.

Immunogen: Crude human uterus extract was used as the immunogen for the Caldesmon antibody.

Storage: Store the Caldesmon antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).