Description
Calbindin Antibody / CALB1 | V7963SAF-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free
Format: Purified
Clone: CALB1/3333
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: ELISA, IHC-P
Buffer: N/A
Limitation: This CALB1 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: The family of EF-hand type Ca2+-binding proteins includes Calbindin D28K, Calbindin D9K, S-100 and, Calgranulin A (also designated MRP8), Calgranulin B (also designated MRP14), Calgranulin C and the Parvalbumin family members, including Parvalbumin and Parvalbumin (also designated oncomodulin). Calbindin D28K, also known as calbindin, CALB1, D-28K or vitamin D-dependent calcium-binding protein, is a 261-amino acid protein with 6 EF-hand domains, 4 of which are active calcium-binding domains. Expressed in brain, ovary, uterus, testis, pancreas, liver, kidney and intestine, Calbindin D28K acts as a calcium-buffering agent and alters the activity of the plasma membrane ATPase. In neuronal cells, Calbindin D28K modulates calcium channel activity, calcium transients and intrinsic neuronal firing activity. Also, Calbindin D28K has been implicated to play a role in apoptosis and microtubule function.
Immunogen: A recombinant human partial protein (amino acids 7-96) was used as the immunogen for this CALB1 antibody.
Storage: Store the CALB1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
