Description
Cadherin 16 Antibody | V3691BTN | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Biotin Conjugate
Clone: CDH16/2125
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: ELISA, WB, IHC-P
Buffer: N/A
Limitation: This CDH16 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport.It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells.Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
Immunogen: A portion of amino acids 371-507 from the human protein was used as the immunogen for the CDH16 antibody.
Storage: Store the CDH16 antibody at 2-8oC (up to one month) or aliquot and store at -20 °C (longer term).
