Description
Cadherin 10 Antibody / CDH10 | F54699-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: WB, FACS, IHC-P
Buffer: N/A
Limitation: This Cadherin 10 antibody is available for research use only.
Purity: Antigen affinity purified
Description: CDH10 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance.
Immunogen: A portion of amino acids 495-523 from the human protein was used as the immunogen for the Cadherin 10 antibody.
Storage: Aliquot the Cadherin 10 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
