CA9 Monoclonal Antibody | E-AB-22034

CA9 Monoclonal Antibody | E-AB-22034 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human

Host: Mouse

Isotype: IgG

Application: WB, IHC-p, IF

Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction

Background: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic Peptide

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification: Protein A purification

Dilution: WB 1:1000-1:3000, IHC 1:50-300, IF 1:50-1:200

Conjugation: Unconjugated

Calculated Molecular Weight: 50 kDa

Observed Molecular Weight: 35-38 kDa

Clonality: Monoclonal