Description
CA9 Monoclonal Antibody | E-AB-22034 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human
Host: Mouse
Isotype: IgG
Application: WB, IHC-p, IF
Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction
Background: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation.
Lead Time: 7~10 days
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic Peptide
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification: Protein A purification
Dilution: WB 1:1000-1:3000, IHC 1:50-300, IF 1:50-1:200
Conjugation: Unconjugated
Calculated Molecular Weight: 50 kDa
Observed Molecular Weight: 35-38 kDa
Clonality: Monoclonal
