Description
C8orf4 Polyclonal Antibody | E-AB-18766 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Application: IHC, ELISA
Research Area: Cancer, Epigenetics and Nuclear Signaling, Signal transduction, Stem cells
Background: This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.
Lead Time: 7~10 days
Concentration: 0.96 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human C8orf4
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification: Antigen affinity purification
Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000
Conjugation: Unconjugated
Calculated Molecular Weight: N/A
Observed Molecular Weight: N/A
Clonality: Polyclonal
