Description
c-Myc Antibody | V7971SAF-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free
Format: Purified
Clone: MYC2895R
Host: Rabbit
Clonality: Recombinant Rabbit Monoclonal
Isotype: Rabbit IgG, kappa
Species Reactivity: Human
Application: ELISA, FACS
Application Details: ELISA (order BSA-free format for coating),Flow cytometry: 1-2ug/million cells in 0.1ml
Application Note: Optimal dilution of the antibody should be determined by the researcher.
Purity: Protein A affinity chromatography
Description: It recognizes a transcription factor of 64-67kDa, identified as c-myc. Its epitope spans between aa 410-419 (EQKLISEEDL) which is a specific portion of an alpha helical region of human c-myc protein. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease.
Immunogen: Amino acids 408-439 were used as the immunogen for the recombinant c-Myc antibody. The specific epitope has been localized to amino acids 410-419 (EQKLISEEDL).
Storage: Store the recombinant c-Myc antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
Localization: N/A
