c-Myc Antibody | V7971-100UG

c-Myc Antibody | V7971-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: MYC2895R

Host: Rabbit

Clonality: Recombinant Rabbit Monoclonal

Isotype: Rabbit IgG, kappa

Species Reactivity: Human

Application: ELISA, FACS

Application Details: ELISA (order BSA-free format for coating),Flow cytometry: 1-2ug/million cells in 0.1ml

Application Note: Optimal dilution of the antibody should be determined by the researcher.

Purity: Protein A affinity chromatography

Description: It recognizes a transcription factor of 64-67kDa, identified as c-myc. Its epitope spans between aa 410-419 (EQKLISEEDL) which is a specific portion of an alpha helical region of human c-myc protein. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease.

Immunogen: Amino acids 408-439 were used as the immunogen for the recombinant c-Myc antibody. The specific epitope has been localized to amino acids 410-419 (EQKLISEEDL).

Storage: Store the recombinant c-Myc antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).

Localization: N/A