Description
c-Myc Antibody (phospho-T58) | F48482-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS pH 7.4 with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: DB, WB, ELISA
Buffer: N/A
Limitation: This phospho c-Myc antibody is available for research use only.
Purity: Antigen affinity
Description: c-Myc participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia.
Immunogen: This phospho c-Myc antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT58 of human MYC.
Storage: Aliquot the phospho c-Myc antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
