c-Myc(9E10.), CF647 conjugate, 0.1mg/mL Antibody | BNC470596-100

c-Myc(9E10.), CF647 conjugate, 0.1mg/mL Antibody | BNC470596-100| Gentaur Distribution US, UK & Europe

Summary.: The epitope of this antibody spans the Myc tag epitope, aa 410-419 (EQKLISEEDL), which is a specific portion of an alpha helical region of human c-myc protein. Because the epitope is located at the dimerization site of the protein, the antibody is not sensitive for detecting endogenous c-myc, making it suitable for detecting Myc tagged proteins or myc overexpression. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. .

Conjugate: CF647.

Storage Buffer: PBS, 0.1% BSA, 0.05% azide.

Storage Temperature: 2°C to 8°C.

Application: IHC, FFPE (verified).

Stability: Stable at room temperature or 37°C (98°F) for 7 days.