C-ets-2 Antibody / ETS2 | V8921-20UG

C-ets-2 Antibody / ETS2 | V8921-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: PCRP-ETS2-1D9

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: ELISA, FACS, IF

Buffer: N/A

Limitation: This ETS2 antibody is available for research use only.

Purity: Protein A/G affinity

Description: ETS2 (Protein C-ets-2) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. ETS2 was shown to be mutated in reeler mice, a mutation that is associated with widespread disruption of laminated regions of the brain, leading to impaired motor coordination, tremors and ataxia. ETS2 protein expression is complex and changes throughout development. ETS2 appears to function upstream of Dab1, in a signaling pathway that controls cell positioning in the developing brain, and is also thought to be a direct effector of the neurotrophin BDNF.

Immunogen: Recombinant full-length human ETS2 protein was used as the immunogen for the ETS2 antibody.

Storage: Aliquot the ETS2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.