Description
c-Abl Antibody / Abl1 | F43352-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Mouse
Application: WB, IHC, ELISA
Buffer: N/A
Limitation: This Abl1 antibody is available for research use only.
Purity: Antigen affinity
Description: Abl1 is a protein kinase that regulates key processes linked to cell growth and survival. Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
Immunogen: A portion of amino acids 613-641 from the mouse protein was used as the immunogen for this Abl1 antibody.
Storage: Aliquot the Abl1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
