Description
BtRf-BetaCoV/JL2012 Spike Trimer Protein (R648A, KV949-950PP), His Tag | SPN-S52Hs-50ug| Gentaur Distribution US, UK & Europe
It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Source: BtRf-BetaCoV/JL2012 Spike Trimer, His Tag (SPN-S52Hs) is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. It contains AA Tyr 16 - Pro 1176 (Accession # A0A0U1UYX4-1 (R648A, KV949-950PP) ).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Tyr 16 - Pro 1176.
Conjugate: Unconjugated.
Molecular Weight: 133.3 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 133.3 kDa. The protein migrates as 160-190 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: PBS.
Storage Conditions: -20℃.
Shipping Conditions: RT
