BRCA1 (Breast Marker)(BRCA1/2985), CF405S conjugate, 0.1mg/mL Antibody | BNC042985-100

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SKU:
37-BNC042985-100
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IN STOCK
Weight:
1.00 KGS
€418.00
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BRCA1 (Breast Marker)(BRCA1/2985), CF405S conjugate, 0.1mg/mL Antibody | BNC042985-100| Gentaur Distribution US, UK & Europe

Summary.: BRCA1 is a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. It combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). BRCA1 associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. .

Conjugate: CF405S.

Storage Buffer: PBS, 0.1% BSA, 0.05% azide.

Storage Temperature: 2°C to 8°C.

Application: .

Stability: Stable at room temperature or 37°C (98°F) for 7 days.

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Additional Information

Size:
100 uL
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