Description
BMX, GST-tag | 40402 | Gentaur US, UK & Europe Disrtribition
Category: Kinase/Cytoplasmic Tyrosine
Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Background: The BMX gene encodes a non-receptor tyrosine kinase, which may play a role in the growth and differentiation of hematopoietic cells (1). The BMX gene is located on chromosomal band Xp22.2 between the DXS197 and DXS207 loci. Interestingly, chromosome X also contains the closest relative of BMX, the BTK gene, implicated in X-linked agammaglobulinemia. BMX, is found to induce activation of the Stat signaling pathway (2).
Description: Recombinant full-length human cytoplasmic tyrosine-protein kinase BMX (BMX), also known as bone marrow tyrosine kinase gene in chromosome X protein, epithelial and endothelial tyrosine kinase, ETK, and NTK38 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag, a.a. 1-675 (end). The gene accession number is NM_001721 (variant 2).
Product Type: Protein
Shippement Condition: -80°C
