BMPR2 Antibody | F53750-0.4ML

BMPR2 Antibody | F53750-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: IHC, FACS, ELISA

Buffer: N/A

Limitation: This BMPR2 antibody is available for research use only.

Purity: Purified

Description: BMPR2 is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in BMPR2 have been associated with primary pulmonary hypertension.

Immunogen: A portion of amino acids 27-56 from the human protein was used as the immunogen for this BMPR2 antibody.

Storage: Aliquot the BMPR2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.