Description
BMP4 Antibody / Bone morphogenetic protein 4 | RQ5387 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol
Format: Purified
Clone: BBB-2
Host Animal: Rabbit
Clonality: Rabbit Monoclonal
Species Reactivity: Human
Application: IHC-P, WB
Buffer: N/A
Limitation: This BMP4 antibody is available for research use only.
Purity: Affinity purified
Description: The BMP4 gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. [RefSeq]
Immunogen: A synthetic peptide specific to human BMP4 was used as the immunogen for the BMP4 antibody.
Storage: Store the BMP4 antibody at -20 °C.
