Description
BMP2 Polyclonal Antibody | E-AB-19618 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human
Host: Rabbit
Isotype: IgG
Application: WB, ELISA
Research Area: Cancer, Cardiovascular, Signal Transduction, Stem Cells
Background: Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer, which binds to its receptor. There is also a 40-45 kDa form of BMP2, as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction.
Lead Time: 7~10 days
Concentration: 1.4 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human BMP2
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification: Antigen affinity purification
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000
Conjugation: Unconjugated
Calculated Molecular Weight: 45 kDa
Observed Molecular Weight: Refer to figures
Clonality: Polyclonal
